Addictions are chronic brain diseases that can be treated medically
Opiant is a specialty pharmaceutical company with a mission to create best-in-class medicines for the treatment of addictions and drug overdose.
The numbers
More than 20 million people in the United States live with a substance use disorder, but only 10% of those affected receive treatment for their condition
with emergency room visits with Acute Cannabinoid Overdose
with Alcohol Use Disorder
with Opioid Use Disorder and 70k opioid-related overdose deaths annually in the USA
OPIANT AND SUBSTANCE USE DISORDERS
Our Pipeline
To address the diverse and mounting demands of modern-day substance use, Opiant is advancing a pipeline of scientifically-informed treatment approaches.
Spotlight
The latest from Opiant

Fox Business News: The Evening Edit
May 18, 2022 – in an interview with The Evening Edit, Opiant CEO, Dr Roger Crystal, talks about recent CDC data on drug overdose and why Opiant, the company that created NARCAN Nasal Spray, recently completed clinical trials on a successor the Company believes better tailored to the current public health threat from synthetic opioids.

Cheddar TV: Cheddar Innovation
April 25, 2022 – in an interview with Cheddar TV, Opiant CEO, Dr Roger Crystal speaks with Cheddar TV about how an investigational treatment by Opiant that is undergoing trials in Europe may help people with Alcohol Use Disorder.

Alcohol Awareness Month
April 25, 2022 – in an interview with Varney & Co, Opiant CEO, Dr Roger Crystal, talks about alcohol use disorder and an investigational treatment by Opiant that is undergoing trials in Europe that may help people with this serious condition.
Opiant Pharmaceuticals Announces FDA Acceptance and Priority Review of NDA for OPNT003, Nasal Nalmefene, for Opioid Overdose
FDA sets PDUFA date of May 22, 2023 SANTA MONICA, Calif. , Jan. 19, 2023 (GLOBE NEWSWIRE) — Opiant Pharmaceuticals , Inc. (“Opiant”) (NASDAQ: OPNT) today…
Opiant Pharmaceuticals Announces Completion of Rolling NDA Submission for OPNT003, Nasal Nalmefene, for Opioid Overdose
SANTA MONICA, Calif. , Nov. 22, 2022 (GLOBE NEWSWIRE) — Opiant Pharmaceuticals , Inc. (“Opiant”) (NASDAQ: OPNT) today announced it has completed submission of its rolling…
Opiant Pharmaceuticals Announces Third Quarter 2022 Financial Results
SANTA MONICA, Calif. , Nov. 14, 2022 (GLOBE NEWSWIRE) — Opiant Pharmaceuticals , Inc. (“Opiant”) (NASDAQ: OPNT), a specialty pharmaceutical company developing medicines to treat addictions…
Treatment of overdose in the synthetic opioid era
Published in October 2021 by Pharmacology & Therapeutics.
Cannabinoid1 (CB‐1) receptor antagonists: a molecular approach to treating acute cannabinoid overdose
Published in 2020 by the Journal of Neural Transmission.
Fighting fire with fire: development of intranasal nalmefene to treat synthetic opioid overdose
Published in April 2019 by ASPET Journals.
Lessons from a doctor and CEO on the US’s opioid crisis
April 14, 2020 – Roger Crystal set out to impact healthcare at a ‘societal’ level. The doctor who developed the NARCAN® Nasal Spray says he is proud to see its impact on the opioid crisis in the United States: the opioid overdose reversal medicine has saved a large number of lives.
Opiant donates to organizations supporting patients vulnerable to substance use disorders during COVID-19
Opiant donated $40,000 to the International Association of Fire Fighters Foundation, the Association of Recovery in Higher Education, the Harm Reduction Coalition and the UK’s Action on Addiction.
A Prescription for Tackling the Opioid Overdose Crisis – A Panel Discussion
May 25, 2021 – A panel of experts agreed that to save lives amid the escalating overdose crisis, we must improve education about addiction and overdose, eliminate stigma and rapidly advance co-prescribing of reversal agents.

Neighbors Helping Neighbors: Empowering Individuals to Help Stop the Opioid Epidemic
Clockwise from top left: Sen. Ralph Alvarado (R-KY-28), Lt. Patrick Glynn (MA), Overdose Lifeline’s Justin Phillips and Shatterproof’s Kevin Roy discuss the important role of…

A Sister’s View on Substance Use Disorder: Care, Love, and Recovery
Substance use disorders (SUD) often impact an entire family, not just the person with the condition. Recently, we spoke with Jessica, a member of the…

A Prescription for Tackling the Opioid Overdose Crisis
“You cannot recover if you are not alive.” Clockwise from top left: Dr. Stephen Loyd, Dr. Kevin Zacharoff, Assemblyman John Armato and Shatterproof’s Courtney Hunter talk…