Dr. O’Malley is a Professor and the Deputy Chair for Clinical Research in the Department of Psychiatry at the Yale University School of Medicine. She is the Director of the Division of Substance Abuse Research in the Department of Psychiatry at the Yale University School of Medicine. The major focus of her research is on the development of more effective treatments for substance use disorders, primarily alcohol and tobacco. Dr. O’Malley’s landmark study on the efficacy of naltrexone was pivotal to the approval of this medication by the Food and Drug Administration for use in the treatment of alcoholism in 1994. She has continued to study the efficacy of opiate antagonists and other pharmacotherapies using human laboratory paradigms and clinical trials.
Dr. O’Malley was President of the Research Society on Alcoholism from 2001-2003. She received the Joel Elkes International Award for Exceptional Contributions to Psychopharmacology from the American College of Neuropsychopharmacology, the Dan Anderson Research Award from the Hazelden Foundation, the Betty Ford Award from the Association for Medical Education and Research in Substance Abuse, and an American Psychological Association Presidential Citation for leadership and research in the field of addictions. She served on the National Advisory Council on Alcohol Abuse and Alcoholism of the National Institutes of Health from November 2002 – March 2007. She serves on several editorial boards, including JAMA Psychiatry.